| CatalogCode: | | NB100-65394 |
| ProductName: | | CD7 Antibody |
| Product Description: | | Mouse Monoclonal anti-CD7 (LT7) |
| Clone: | | LT7 |
| Clonality: | | Monoclonal |
| Immunogen: | | Normal human peripheral blood lymphocytes |
| Specificity: | | NB100-65394 is a single chain cell surface glycoprotein of 40kD, expressed by T cells, NK cells and thymocytes. CD7 is also expressed by tumour cells in some cases of acute myeloid leukaemia. |
| CrossReactivity: | | Human. Not yet tested in other species. |
| Packaging: | | 0.2 mg protein A purified Mouse ascites. |
| Uses: | | This antibody is useful for Immunohistochemistry-Frozen, immunoprecipitation, flow cytometry / FACS analysis |
| Localization: | | Cell Membrane |
| Background: | | CD7 is a 40 kDa transmembrane, single-chain glycoprotein, which is a member of the immunoglobulin superfamily. CD7 is expressed by the majority of thymocytes and mature T cells, NK cells and pre-B cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. The function of CD7 is not yet known although cross-linking of CD7 with antibodies induces a T cell transmembrane calcium flux and CD7 expression is induced by ionomycin. The CD7 molecule has been reported to be the receptor for the IgM-Fc portion (FcR mu) on the surface of T cells. |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | | protein A purified |
| Isotype: | | IgG2a |
| Host_Name: | | Mouse |
| Buffer: | | Phosphate buffered saline pH7.4 |
| ListPrice: | | 295 |
| AppSummary: | | IHC-Fr, IP, FACS |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-CD 7 antibody, anti-CD7 antigen antibody, anti-CD7 molecule antibody, anti-GP 40 antibody, anti-GP40 antibody, anti-LEU 9 antibody, anti-LEU9 antibody, anti-p41 antibody, anti-p41 protein antibody, anti-T cell antigen CD7 antibody, anti-T cell antigen CD7 precursor antibody, anti-T cell leukemia antigen antibody, anti-Tp 40 antibody, anti-TP 41 antibody, anti-Tp40 antibody, anti-TP41 antibody |
| ProteinTarget: | | CD7 |
| PackageSize: | | 0.2 mg |
| more information: | | company product webpage |
|