| CatalogCode: | NB100-65198 |
| ProductName: | CORTICOTROPHIN RELEASING FACTOR Antibody |
| Product Description: | Mouse Monoclonal anti-CORTICOTROPHIN RELEASING FACTOR (4H9) |
| Clone: | 4H9 |
| Clonality: | Monoclonal |
| Immunogen: | Corticotrophin Releasing Factor conjugated to Bovine Serum Albumin |
| Specificity: | NB100-65050 is specific for corticotrophin releasing factor (CRF), a hormone found mainly in the hypothalamus that regulates the release of corticotrophin from the pituitary gland.The unique lysine residue (Lys-36) is likely to be involved in the antigenic determinant as lysine modification by CA blocks binding completely. Human serum, containing CRF-binding protein, also inhibits the binding of this antibody to CRF. |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.2 mg protein G purified Mouse ascites. |
| Uses: | This antibody is useful for Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, ELISA |
| Localization: | Secreted |
| Background: | CRF precursor is a 41-amino acid peptide derived from a 196-amino acid preprohormone. CRF is a neuroendocrine hormone secreted by the paraventricular nucleus (PVN) of the hypothalamus and is a key player in the hypothalamic pituitary adrenal axis. It is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. Neuronal CRF is important in a variety of diverse roles including, memory, depression, stress, kidney function, parturition, metabolism and feeding (to mention a few). |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Phosphate buffered saline, pH 7.2 |
| ListPrice: | 295 |
| AppSummary: | ELISA, IHC-P, IHC-Fr |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Corticoliberin precursor antibody, anti-Corticotropin releasing factor antibody, anti-Corticotropin releasing hormone antibody, anti-Corticotropin releasing hormone deficiency included antibody, anti-crf antibody, anti-crh antibody, anti-crh deficiency included antibody |
| ProteinTarget: | CORTICOTROPHIN RELEASING FACTOR |
| PackageSize: | 0.2 mg |