| CatalogCode: | NB100-65134 |
| ProductName: | hCG Antibody |
| Product Description: | Rabbit Polyclonal anti-hCG |
| Clonality: | Polyclonal |
| Immunogen: | Beta subunit of human choronic gonadotrophin |
| Specificity: | NB100-65134 recognises human chorionic gonadotrophin (hCG), a 30kD hormone produced by placental syncytiotrophoblasts. hCG acts to maintain the corpus luteum until the developing placenta is able to produce the required levels of oestrogen and progesterone.hCG shares a common alpha chain with the pituitary hormones FSH, TSH and LH, but has a unique beta chain which is recognised by this antibody.This antibody stains trophoblastic cells in normal placental, neoplastic trophoblasts of choriocarcinomas and also some cells in breast carcinomas. |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 6 ml of Serum liquid |
| Uses: | This antibody is useful for Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin |
| Localization: | Secreted |
| Control: | Placenta |
| Background: | Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Phosphate buffered saline |
| ListPrice: | 285 |
| AppSummary: | IHC-Fr, IHC-P |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Anterior pituitary glycoprotein hormones common subunit alpha antibody, anti-CG ALPHA antibody, anti-CG beta a antibody, anti-CG beta antibody, anti-CGA antibody, anti-CGB antibody, anti-CGB1 antibody,anti-CGB2 antibody , anti-CGB3 antibody,anti-CGB5 antibody , anti-CGB7 antibody, anti-CGB8 antibody, anti-Choriogonadotropin alpha chain antibody, anti-Choriogonadotropin subunit beta antibody, anti-Chorionic gonadotrophin alpha subunit antibody, anti-Chorionic gonadotrophin chain beta antibody, anti-Chorionic gonadotropin alpha polypeptide antibody, anti-Chorionic gonadotropin beta 3 subunit antibody, anti-Chorionic gonadotropin beta 5 subunit antibody, anti-Chorionic gonadotropin beta 7 subunit antibody, anti-Chorionic gonadotropin beta 8 subunit antibody, anti-Chorionic gonadotropin beta chain antibody, anti-Chorionic gonadotropin beta polypeptide 1 antibody, anti-Chorionic gonadotropin beta polypeptide 2 antibody, anti-Chorionic gonadotropin beta polypeptide 5 antibody, anti-Chorionic gonadotropin beta polypeptide 7 antibody, anti-Chorionic gonadotropin beta polypeptide antibody, anti-Chorionic gonadotropin beta subunit antibody, anti-Follicle stimulating hormone alpha chain antibody, anti-Follitropin alpha chain antibody, anti-FSH alpha antibody, anti-FSHA antibody, anti-Glycoprotein hormones alpha chain precursor antibody, anti-Glycoprotein hormones alpha polypeptide antibody, anti-GPHA 1 antibody, anti-GPHa antibody, anti-GPHA1 antibody, anti-hCGB antibody, anti-Human Chorionic Gonadotropin antibody, anti-LHA antibody, anti-LSH alpha antibody, anti-Luteinizing hormone alpha chain antibody, anti-Lutropin alpha chain antibody, anti-MGC119822 antibody, anti-Thyroid stimulating hormone alpha chain antibody, anti-Thyrotropin alpha chain antibody, anti-TSH alpha antibody, anti-TSHA antibody |
| ProteinTarget: | hCG |
| PackageSize: | 6 ml |
| NotesMain: | Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. |
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