| CatalogCode: | NB100-64804 |
| ProductName: | CD29 Antibody |
| Product Description: | Mouse Monoclonal anti-CD29 (JB1B) |
| Clone: | JB1B |
| Clonality: | Monoclonal |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.2 mg of Ig Fraction |
| Uses: | This antibody is useful for Immunohistochemistry-Frozen, ELISA, Western Blot, flow cytometry / FACS analysis, immunoprecipitation |
| Background: | Integrin beta 1, also known as CD29, is a 130 kDa transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits (including alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, and alpha 6, also known as CD49a, CD49b, CD49c, CD49d, CD49e, and CD49f, respectively) to form the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis, and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. These heterodimeric receptors bridge the cytoplasmic actin cytoskeleton with proteins present in the extracellular matrix and/or on adjacent cells. The clustering of integrins on a cell surface leads to the formation of focal contacts. Interactions between integrins and the extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | IgG Purified |
| Isotype: | IgG2a |
| Host_Name: | Mouse |
| ListPrice: | 325 |
| AppSummary: | IHC-Fr, ELISA, WB, FACS, IP |
| SpeciesSummary: | Hu |
| ProteinTarget: | CD29 |
| PackageSize: | 0.2 mg |
order or
more information: | company product webpage |
| request information: |
|
|