| CatalogCode: | NB100-64650 |
| ProductName: | SOMATOSTATIN Antibody |
| Product Description: | Rat Monoclonal anti-SOMATOSTATIN (YC7) |
| Clone: | YC7 |
| Clonality: | Monoclonal |
| Immunogen: | Somatostatin conjugated to thyroglobulin. |
| Specificity: | NB100-64650 is specific for somatostatin. A hormone involved in endocrine system regulation through interactions with pituitary growth hormone, thyroid stimulating hormone, and a number of hormones of the gastrointestinal tract. Somatostatin has active 14 amino acid and 28 amino acid forms, produced by alternate cleavage of the gene product.This antibody does not cross react with enkephalins, other endorphins, substance P, or CGRP. It partially cross reacts with somatostatin fragments.The epitope recognised by this antibody lies within the 1-14 amino acid sequence of cyclic somatostatin. |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.2 ml of Tissue Culture Supernatant. |
| Uses: | This antibody is useful for Immunohistochemistry-Frozen |
| Localization: | Secreted |
| Background: | The cyclic tetradecapeptide somatostatin is widely distributed throughout the body and is an important regulator of endocrine and nervous system function. It exerts its biologic actions by binding to specific high affinity receptors on the cell surface. Somatostatin inhibits the release of somatotropin. Somatostatin has also been shown in sympathetic nerves, mucosal cells, myenteric nerves of the gastrointestinal tract, salivary glands and in some parafollicular cells of the thyroid. Somatostatin positive cells may also be present in medullary thyroid carcinomas, C cell hyperplasia, thymic and lung tumors and pulmonary small cell carcinomas. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | Tissue culture supernatant |
| Isotype: | IgG2b |
| Host_Name: | Rat |
| ListPrice: | 285 |
| AppSummary: | IHC-Fr |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Growth hormone release inhibiting factor antibody, anti-Somatostatin 28 antibody |
| ProteinTarget: | SOMATOSTATIN |
| PackageSize: | 0.2 ml |
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