| CatalogCode: | NB100-64628 |
| ProductName: | KERATIN 7 Antibody |
| Product Description: | Mouse Monoclonal anti-KERATIN 7 (C35) |
| Clone: | C35 |
| Clonality: | Monoclonal |
| Immunogen: | Native |
| Specificity: | Reacts with keratin 7 expressed in simple epithelial cells and carcinomas derived from simple epithelial tissue. Reacts with an unknown antigen specific to keratin 7. |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.2 mg protein A purified Mouse ascites. |
| Uses: | This antibody is useful for Immunohistochemistry-Frozen |
| Background: | Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are designated 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. Cytokeratin 7 is a 54kD intermediate filament protein found in a variety of glandularepithelia. Cytokeratin 7 has been found in columnar and glandular epithelium of the lung, cervix, breast, bile ducts and larger collecting ducts of the kidney. It is present in the transitional epithelium of bladder as well as ovarian and lungepithelia, and occasionally staining of blood vessel cell walls, particularly endothelial cells, may be observed. However, Cytokeratin 7 is not expressed by epithelial cells of the gastrointestinal tract, colon or prostate. Keratin 7 is often co expressed with keratin 19. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein A purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Phosphate buffered saline, pH 7.2 |
| ListPrice: | 285 |
| AppSummary: | IHC-Fr |
| SpeciesSummary: | Hu |
| ALTnames: | anti-CK 7 antibody, anti-ck7 antibody, anti-Cytokeratin7 antibody, anti-K2C7 antibody, anti-K7 antibody, anti-Keratin 55k type ii cytoskeletal antibody, anti-Keratin 7 antibody, anti-Keratin simple epithelial type 1 k7 antibody, anti-Keratin type ii cytoskletal 7 antibody, anti-Keratin7 antibody, anti-KRT 7 antibody, anti-KRT7 antibody, anti-MGC129731 antibody, anti-mgc3625 antibody, anti-Sarcolectin antibody, anti-SCL antibody, anti-Type ii mesothelial keratin k7 antibody |
| ProteinTarget: | KERATIN 7 |
| PackageSize: | 0.2 mg |
order or
more information: | company product webpage |
| request information: |
|
|