| CatalogCode: | NB100-64182 |
| ProductName: | IL-2 Antibody |
| Product Description: | Rat Monoclonal anti-IL-2 (JES6-5H4), conjugated to PE |
| Clone: | JES6-5H4 |
| Clonality: | Monoclonal |
| CrossReactivity: | Mouse. Not yet tested in other species. |
| Packaging: | 100 tests of Purified IgG conjugated to RPE. Liquid. |
| Uses: | This antibody is useful for flow cytometry / FACS analysis |
| Background: | Human interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL-2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | IgG Purified |
| Isotype: | IgG2b |
| Host_Name: | Rat |
| ListPrice: | 285 |
| AppSummary: | FACS |
| SpeciesSummary: | Mu |
| ProteinTarget: | IL-2 |
| PackageSize: | 100 tests |
| Conjugate: | PE |