| CatalogCode: | NB100-64070 |
| ProductName: | CD86 Antibody |
| Product Description: | Mouse Monoclonal anti-CD86 (OX-48), conjugated to PE |
| Clone: | OX-48 |
| Clonality: | Monoclonal |
| CrossReactivity: | Rat. Not yet tested in other species. |
| Packaging: | 100 tests of Purified IgG conjugated to RPE. Liquid. |
| Uses: | This antibody is useful for flow cytometry / FACS analysis |
| Background: | CD86, also known as B72, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell costimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | IgG Purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| ListPrice: | 295 |
| AppSummary: | FACS |
| SpeciesSummary: | Rt |
| ProteinTarget: | CD86 |
| PackageSize: | 100 tests |
| Conjugate: | PE |
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