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| Catalog Code: | NB100-63797 |
| Product Name: | CD43 Antibody |
| Product Description: | Mouse Monoclonal anti-CD43 (W3/13), conjugated to Biotin |
| Clone: | W3/13 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Cross Reactivity: | Rat. Not yet tested in other species. |
| Packaging: | 100 tests of Purified IgG conjugated to Biotin. Liquid. |
| Uses: | This antibody is useful for flow cytometry / FACS analysis |
| Background: | CD43 is one of the major glycoproteins of thymocytes and T lymphocytes, it plays a role in the physicochemical properties of the T cell surface and in lectin binding. CD43 presents carbohydrate ligands to selectins. It has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. The antigen is a counter receptor for SN/Siglec1. During T cell activation CD43 is actively removed from the T cell antigen presenting cell contact site suggesting a negative regulatory role in adaptive immune response. CD43 is expressed by the majority of leucocytes, with the exception of most B cells. However CD43 expression is seen in some cases of B cell lymphocytic lymphoma and centrocytic lymphoma. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | IgG Purified |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Rt |
| Package Size: | 100 tests |
| Preservative: | Sodium Azide |
| Conjugate: | Biotin |
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more information: | company product webpage |