| CatalogCode: | NB100-63722 |
| ProductName: | CD33 Antibody |
| Product Description: | Mouse Monoclonal anti-CD33 (WM53), conjugated to APC |
| Clone: | WM53 |
| Clonality: | Monoclonal |
| Immunogen: | Human AML cells |
| Specificity: | NB100-63722 recognises the human CD33 cell surface glycoprotein, a 67kD molecule expressed by monocytes, granulocyte precursors, myeloid progenitor cells and myeloid leukaemias. |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 100 tests protein G purified Mouse ascites. |
| Uses: | This antibody is useful for flow cytometry / FACS analysis |
| Background: | CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells. The protein is also expressed on, and is a useful marker for, peripheral monocytes. It is also useful for distinguishing myelogenous leukaemia cells from lymphoid or erythroid leukaemias. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Phosphate buffered saline, pH7.4, 1% Bovine Serum Albumin |
| ListPrice: | 295 |
| AppSummary: | FACS |
| SpeciesSummary: | Hu |
| ALTnames: | Anti-CD 33 antibody; Anti-CD33 antigen antibody; Anti-CD33 molecule antibody; Anti-FLJ00391 antibody; Anti-gp67 antibody; Anti-Myeloid cell surface antigen CD33 antibody; Anti-Myeloid cell surface antigen CD33 precursor antibody; Anti-p67 antibody; Anti-Sialic acid binding Ig like lectin 3 antibody; Anti-Sialic acid binding immunoglobulin like lectin 3 antibody; Anti-SIGLEC3 antibody |
| ProteinTarget: | CD33 |
| PackageSize: | 100 tests |
| Conjugate: | APC |
| GeneralRef: | 1. Favaloro, E.J. et al. (1987) Characterisation of monoclonal antibodies to the human myeloid-specific antigen 'gp67' (CD-33). Dis Markers. 5: 215-225. 2. Favaloro, E.J. et al. (1988) Further characterisation of myeloid antigens ('gp160,95', 'gp150' and 'gp67'): Investigation of epitopic heterogeneity and non-haemopoietic distribution using panels of monoclonal antibodies belonging to CD-11b, CD-13 and CD33. Br. J. Haematol. 69: 163-171. |