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| Catalog Code: | NB100-63718 |
| Product Name: | CD322 Antibody |
| Product Description: | Rat Monoclonal anti-CD322 (CRAM-18 F26), conjugated to FITC |
| Clone: | CRAM-18 F26 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 0.1 mg/ml |
| Immunogen: | Recombinant soluble JAM-2 |
| Specificity: | NB100-63718 recognises mouse junctional adhesion molecule-2 (JAM-2), a 45kD transmembrane type 1 protein, a member of the immunoglobulin superfamily otherwise known as CD322. In adult murine tissue, CD322 expression is reported to be restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney. In humans, CD322 expression is not restricted to endothelial cells, but is also expressed on human lymphocytes. |
| Cross Reactivity: | Mouse. Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Rat ascites. |
| Uses: | This antibody is useful for flow cytometry / FACS analysis |
| Localization: | Membrane; single pass type I membrane protein. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG2a |
| Host Name: | Rat |
| Buffer: | Phosphate buffered saline, pH7.4, 1% Bovine Serum Albumin |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Mu |
| Alternate Names: | Anti-C21orf43 antibody; Anti-CAM antibody; Anti-CD322 antigen antibody; Anti-JAM 2 antibody; Anti-JAM B antibody; Anti-JAM IT/VE JAM antibody; Anti-JAM2 antibody; Anti-JAMB antibody; Anti-JAMC antibody; Anti-Junction adhesion molecule B antibody; Anti-Junction adhesion molecule C antibody; Anti-PRO 245 antibody; Anti-PRO245 antibody; Anti-Vascular endothelial junction associated molecule antibody; Anti-VE JAM antibody; Anti-VEJAM antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.09% Sodium Azide |
| Conjugate: | FITC |
| General References: | 1. Aurrand-Lions, M. et al. (2001) Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members. Blood. 98: 3699 - 3707. 2. Johnson-Léger, C.A. et al. (2002) Junctional adhesion molecule - 2 (JAM-2) promotes lymphocyte transendothelial migration. Blood. 100: 2479 - 2486. 3. Aurrand-Lions, M. et al. (2001) JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells. J. Biol. Chem. 276: 2733 - 2741. |
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