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| Catalog Code: | NB100-63706 |
| Product Name: | CD31 Antibody |
| Product Description: | Mouse Monoclonal anti-CD31 (WM59), conjugated to FITC |
| Clone: | WM59 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 0.1mg/ml |
| Specificity: | NB100-63706 recognises the human CD31 cell surface antigen, a 130kD glycoprotein expressed by platelets, endothelial cells, granulocytes and some lymphocytes. CD31 is also known as PECAM-1. |
| Cross Reactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Mouse ascites. |
| Uses: | This antibody is useful for flow cytometry / FACS analysis |
| Localization: | Membrane; single pass type I membrane protein. |
| Background: | CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas). |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | Phosphate buffered saline, pH7.4, 1% Bovine Serum Albumin |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | Anti-CD31 antigen antibody; Anti-Endocam antibody; Anti-GPIIA antibody; Anti-Pecam 1 antibody; Anti-Pecam1 antibody; Anti-Platelet/endothelial cell adhesion molecule antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.09% Sodium Azide |
| Conjugate: | FITC |
| General References: | 1. Carbanas. C., Sanchez-Madrid, F., et al. (1989) Characterisation of a novel myeloid antigen regulated during differentiation of monocytic cells. Eur J. Immunol. 19: 1373-1378. 2. Yoshino, N. et al. (2000) Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp. Anim. 49 (2): 97-110. |
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