| CatalogCode: | NB100-63620 |
| ProductName: | CD244 Antibody |
| Product Description: | Mouse Monoclonal anti-CD244 (2B4.69), conjugated to Biotin |
| Clone: | 2B4.69 |
| Clonality: | Monoclonal |
| Specificity: | NB100-63620 is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4).The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells.CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family. |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Mouse ascites. |
| Uses: | This antibody is useful for flow cytometry / FACS analysis |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Phosphate buffered saline, pH7.4, 1% Bovine Serum Albumin |
| ListPrice: | 295 |
| AppSummary: | FACS |
| SpeciesSummary: | Hu |
| ALTnames: | Anti-2B4 antibody; Anti-CD244 molecule natural killer cell receptor 2B4 antibody; Anti-h2B4 antibody; Anti-NAIL antibody; Anti-Natural killer cell receptor 2B4 antibody; Anti-NK cell activation inducing ligand antibody; Anti-NK cell type I receptor protein 2B4 antibody; Anti-NKR2B4 antibody; Anti-Nmrk antibody; Anti-p38 antibody; Anti-SLAMF4 antibody |
| ProteinTarget: | CD244 |
| PackageSize: | 0.1 mg |
| Conjugate: | Biotin |
| GeneralRef: | 1. Romero, X. et al. (2005) CD229 (Ly5) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. J. Immunol. 174: 7033-7042. |