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| Catalog Code: | NB100-63529 |
| Product Name: | CD1a Antibody |
| Product Description: | Mouse Monoclonal anti-CD1a (NA1/34-HLK), conjugated to FITC |
| Clone: | NA1/34-HLK |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 0.1 mg/ml |
| Immunogen: | Human thymocytes |
| Specificity: | NB100-63529 recognises the human CD1a cell surface glycoprotein, a 49kD molecule expressed in association with beta 2 microglobulin. CD1a is expressed strongly by cortical thymocytes, and also by Langerhans cells and interdigitating cells. This product is routinely tested in flow cytometry on MOLT4 cells. |
| Cross Reactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Mouse ascites. |
| Uses: | This antibody is useful for flow cytometry / FACS analysis |
| Localization: | Cell Membrane; type I membrane protein. |
| Background: | All CD1 molecules, except CD1e, are cell surface glycoproteins that are structurally related to the MHC molecules, however, in distinction, CD1 proteins are essentially non polymorphic. CD1 has considerable structural homology with both MHC class I and class II molecules, and CD1 molecules are involved in T cell activation. In contrast to MHC, however, CD1 molecules appear to present predominantly non peptide molecules originating from lipids and glycolipids. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG2a |
| Host Name: | Mouse |
| Buffer: | Phosphate buffered saline, pH7.4, 1% Bovine Serum Albumin |
| Application Summary: | flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | Anti-CD1 antibody; Anti-CD1A Antigen antibody; Anti-CD1a molecule antibody; Anti-Cortical thymocyte antigen CD1A antibody; Anti-Epidermal dendritic cell marker CD1a antibody; Anti-FCB 6 antibody; Anti-FCB6 antibody; Anti-HTA 1 antibody; Anti-HTA1 antibody; Anti-hTa1 thymocyte antigen antibody; Anti-R4 antibody; Anti-T Cell Surface Antigen Leu 6 antibody; Anti-T Cell Surface Antigen T6 antibody; Anti-T cell surface antigen T6/Leu 6 antibody; Anti-T Cell Surface Glycoprotein CD1A antibody; Anti-T6 antibody; Anti-Thymocyte Antigen CD1A antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.09% Sodium Azide |
| Conjugate: | FITC |
| General References: | 1. McMichael, A. J. et al. (1979) A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody. Eur. J. Immunol. 9: 205-210. 2. Poulter, L. W. et al. (1986) Discrimination of human macrophages and dendritic cells by means of monoclonal antibodies. Scand. J. Immunol. 24:351-357. 3. Galkowska, H. et al. (1996) Reactivity of antibodies directed against human antigens with surface markers on canine leucocytes. Vet. Immunol. Immunopathol. 53: 329-334. 4. Yoshino, N. et al. (2000) Upgrading of flow ctometric analysis for absolute counts, cytokines and other antigenic molecules of Cynomolgus monkeys (Macaca fascicularis) by using anti-human cross reactive antibodies. Exp. Anim. 49: 97-110. |
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