| CatalogCode: | NB100-63450 |
| ProductName: | CD151 Antibody |
| Product Description: | Mouse Monoclonal anti-CD151 (11G5a), conjugated to FITC |
| Clone: | 11G5a |
| Clonality: | Monoclonal |
| Specificity: | NB100-63450 recognises the human CD151 cell surface antigen, also known as PETA-3. CD151 is expressed by epithelial cells, endothelial cells, platelets, megakaryocytes, monocytes and in the renal glomeruli and proximal and distal tubules. CD151 is not expressed by lymphocytes or granulocytes. More recently CD151 has also been shown to be expressed by erythrocytes, and to carry the MER2 blood group antigen (2).It should be noted that CD151 is very closely associated with the alpha3 beta1 integrin in cells and co-immunoprecipitation may occur even in quite stringent conditions (1). |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Mouse ascites. |
| Uses: | This antibody is useful for flow cytometry / FACS analysis |
| Localization: | Cell Membrane; multi pass membrane protein. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | 1% Bovine Serum Albumin |
| ListPrice: | 295 |
| AppSummary: | FACS |
| SpeciesSummary: | Hu |
| ALTnames: | Anti-CD151 antigen antibody; Anti-CD151 molecule (Raph blood group) antibody; Anti-GP27 antibody; Anti-Human platelet endothelial tetraspan antigen 3 mRNA complete cds antibody; Anti-Membrane glycoprotein SFA1 antibody; Anti-MER2 antibody; Anti-PETA 3 antibody; Anti-PETA3 antibody; Anti-Platelet endothelial tetraspan antigen 3 antibody; Anti-RAPH antibody; Anti-SFA 1 antibody; Anti-SFA1 antibody; Anti-Tetraspanin 24 antibody; Anti-Tetraspanin24 antibody; Anti-Tspan 24 antibody; Anti-TSPAN24 antibody |
| ProteinTarget: | CD151 |
| PackageSize: | 0.1 mg |
| Conjugate: | FITC |
| GeneralRef: | 1. Yauch, R.L. et al. (1998) Highly stoichiometric, stable, and specific association of integrin alpha 3 beta 1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration. Mol. Cell. Biol. 9: 2751-2765. 2. Crew, V.K. et al. (2004) CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin. Blood 104:2217-2223. |
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