| CatalogCode: | NB100-63427 |
| ProductName: | CD142 Antibody |
| Product Description: | Mouse Monoclonal anti-CD142 (CLB/TF-5), conjugated to FITC |
| Clone: | CLB/TF-5 |
| Clonality: | Monoclonal |
| Specificity: | NB100-63427 recognises human CD142, a 45kD cell surface glycoprotein which is otherwise known as Tissue Factor (TF). CD142 expression can be induced on monocytes, macrophages and endothelial cells by various stimuli including interleukin 1, tumour necrosis factor and endotoxin. CD142 initiates the blood clotting cascade by binding coagulation factor VIIa, which activates factor IX or factor X by specific limited proteolysis. CD142 also plays an important role in inflammation, angiogenesis, and the pathophysiology of atherosclerosis and cancer.The CLB/TF-5 antibody has been used successfully in an ELISA assay as a coating antibody in association with clone CLB/TF-1, which recognises a different epitope of CD142. (1) |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.1 mg protein A purified Mouse ascites. |
| Uses: | This antibody is useful for flow cytometry / FACS analysis |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein A purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | TRIS buffered saline, pH 8.0, 1% Bovine Serum Albumin |
| ListPrice: | 285 |
| AppSummary: | FACS |
| SpeciesSummary: | Hu |
| ALTnames: | Anti-CD142 antigen antibody; Anti-Coagulation factor III antibody; Anti-F3 antibody; Anti-TF antibody; Anti-TFA antibody; Anti-Thromboplastin antibody |
| ProteinTarget: | CD142 |
| PackageSize: | 0.1 mg |
| Conjugate: | FITC |
| GeneralRef: | 1. van der Putten, R.F. et al. (2005) High-affinity antibodies in a new immunoassay for plasma tissue factor: reduction in apparent intra-individual variation. Clin. Chem. Lab. Med. 43:1386 - 1391. |
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