| CatalogCode: | NB100-63312 |
| ProductName: | CD10 Antibody |
| Product Description: | Mouse Monoclonal anti-CD10 (SN5c), conjugated to Biotin |
| Clone: | SN5c |
| Clonality: | Monoclonal |
| Immunogen: | Partially purified cell membrane antigens from fresh leukemia cells. |
| Specificity: | NB100-63312 recognises the human CD10 cell surface antigen, a 100kD glycoprotein expressed by acute lymphoblastic leukaemia cells and by peripheral blood granulocytes. CD10 is also known as the Common Acute Lymphoblastic Leukaemia Antigen (CALLA). |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Mouse ascites. |
| Uses: | This antibody is useful for flow cytometry / FACS analysis |
| Localization: | Type II membrane protein. |
| Background: | CD10, also known as the Common Acute Lymphocytic Leukemia Antigen (CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, immature B cells with in adult bone marrow and on cells from patients with chronic myelocytic leukemia (CML). CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Phosphate buffered saline, pH7.4, 1% Bovine Serum Albumin |
| ListPrice: | 295 |
| AppSummary: | FACS |
| SpeciesSummary: | Hu |
| ALTnames: | Anti-Atriopeptidase antibody; Anti-CALLA antibody; Anti-CD 10 antibody; Anti-CD10 antigen antibody; Anti-Common acute lymphocytic leukemia antigen antibody; Anti-DKFZp686O16152 antibody; Anti-Enkephalinase antibody; Anti-EPN antibody; Anti-gp100 antibody; Anti-Membrane metallo endopeptidase antibody; Anti-Membrane metalloendopeptidase antibody; Anti-MGC126681 antibody; Anti-MGC126707 antibody; Anti-MME antibody; Anti-NEP antibody; Anti-Neprilysin antibody; Anti-Neutral endopeptidase 24.11 antibody; Anti-Neutral endopeptidase antibody |
| ProteinTarget: | CD10 |
| PackageSize: | 0.1 mg |
| Conjugate: | Biotin |
| GeneralRef: | 1. Matsuzaki, H. et al. (1987) Unique epitopes of common acute lymphoblastic leukemia antigen detected by new monoclonal antibodies. Cancer Res. 47: 2160-2166. 2. Biddle, W.C. et al. (1989) in vitro and in vivo cytotoxic activity of anti-human leukemia monoclonal antibodies SN5c and SN6 daunorubicin conjugates. Leuk. Res. 13: 699-707. |