| CatalogCode: | NB100-63292 |
| ProductName: | SYNAPTOBREVIN Antibody |
| Product Description: | Mouse Monoclonal anti-SYNAPTOBREVIN (SP11) |
| Clone: | SP11 |
| Clonality: | Monoclonal |
| Immunogen: | Crude human synaptic immunoprecipitate |
| Specificity: | NB100-63292 appears to recognise the human synaptic vesicle protein synaptobrevin, VAMP, (3., 6.). |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.2 mg protein G purified Mouse ascites. |
| Uses: | This antibody is useful for ELISA, Western Blot, Immunohistochemistry-Paraffin |
| Localization: | Type IV membrane protein. Neuronal synaptic vesicles. Isoform VAMP-1B is found in mitochondria. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Phosphate buffered saline, pH7.2 |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB, IHC-P |
| SpeciesSummary: | Hu |
| ALTnames: | Anti-SYB antibody; Anti-VAMP antibody; Anti-Vesicle associated membrane protein antibody |
| ProteinTarget: | SYNAPTOBREVIN |
| PackageSize: | 0.2 mg |
| GeneralRef: | 1. Honer, W.G. et al. (1994) Hippocampal synaptic pathology in patients with temporal lobe epilepsy. Acta Neuropathol. 87: 202-210. 2. Honer, W.G. et al. (1992) Regional synaptic pathology in Alzheimer's disease. Neurobiol. Aging. 13: 375-382. 3. Honer, W.G. et al. (1993) Human synaptic proteins with a heterogeneous distribution in cerebellum and visual cortex. Brain Res. 609: 9-20. 4. Honer, W.G. et al. (1992) Characterization of a synaptic antigen of interest in neuropsychiatric illness. Biol. Psychiatry 31: 147-158. 5. Honer, W.G. et al. (1989) Monoclonal antibodies to study the brain in schizophrenia. Brain Res. 500: 379-383. 6. Masliah, E. et al. (1994) Topographical distribution of synaptic-associated proteins in the neuritic plaques of Alzheimer's disease hippocampus. Acta Neuropathol. 87: 135-142. 7. Simpson, I.A. et al. (1994) Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease. Ann. Neurol. 35: 546-551. 8. Wakabayashi, K. et al. (1994) Synapse alterations in the hippocampalentorhinal formation in Alzheimer's disease with and without Lewy body disease. Brain Res. 667: 24-32. 9. Dickson, D.W. et al. (1994) Hippocampal sclerosis: a common pathological feature of dementia in very old (>80 years of age) humans. Acta Neuropathologica 88: 212-221. 10. Dickson, D.W. et al. (1995) Correlations of synaptic markers with cognitive status in prospectively studied elderly humans. Neurobiol. Aging 16: 285-98. |
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