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| Catalog Code: | NB100-63289 |
| Product Name: | MAST CELL CHYMASE Antibody |
| Product Description: | Mouse Monoclonal anti-MAST CELL CHYMASE (CC1) |
| Clone: | CC1 |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Concentration: | 1.0 mg/ml |
| Immunogen: | Purified human skin chymase |
| Specificity: | NB100-63289 binds to human mast cell chymase, an important marker of mast cells and also an important mediator of inflammation. NB100-63289 may be used to detect mast cells in routinely fixed tissues, and has been used to study the distribution of mast cells in skin, synovium, lung and heart. Binding of NB100-63289 to chymase is not reduced in the presence of heparin, suggesting that the antibody does not bind to the heparin-binding domain of chymase. |
| Cross Reactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Mouse ascites. |
| Uses: | This antibody is useful for ELISA, Western Blot, Immunohistochemistry-Paraffin |
| Localization: | Secreted. Cytoplasmic granule. Mast cell granules. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | Phosphate buffered saline, pH7.4 |
| Application Summary: | ELISA, Western Blot, Immunohistochemistry-Paraffin |
| Species Summary: | Hu |
| Alternate Names: | Anti-Chymase 1 antibody; Anti-Chymase 1 mast cell antibody; Anti-Chymase antibody; Anti-Chymase heart antibody; Anti-Chymase mast cell antibody; Anti-Chymase1 antibody; Anti-CMA 1 antibody; Anti-CMA1 antibody; Anti-CMA1 protein antibody; Anti-CYH antibody; Anti-CYM antibody; Anti-EC 3.4.21.39 antibody; Anti-Mast cell protease I antibody; Anti-MCT 1 antibody; Anti-MCT1 antibody; Anti-MGC119890 antibody; Anti-MGC119891 antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.09% Sodium Azide |
| General References: | 1. Buckley, M.G. et al. (1999) The detection of mast cell subpopulations in formalin-fixed human tissues using a new monoclonal antibody specific for chymase. J. Pathol. 189: 138-143. |
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