| CatalogCode: | NB100-63287 |
| ProductName: | CD230 Antibody |
| Product Description: | Goat Polyclonal anti-CD230 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide corresponding to amino acids 79-97 of the N-terminus of human prion protein |
| Specificity: | Prion protein was classified as CD230 at the 7th HLDA workshop. CD230 is a large membrane protein expressed normally in neurons, and thought to be involved in synaptic transmission. In certain diseases, most notably Creutzfeld-Jakob disease (CJD) and bovine spongiform encephalopathy (BSE), normal prion protein (PrPc) is transformed into an altered, pathogenic, form (PrPsc). This altered form is resistant to proteolytic degradation and accumulates in the brains of affected individuals.NB100-63287 has been shown to stain PrPsc plaques in formalin fixed sections of CJD brain. It also reacts with normal prion protein (PrPc). |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.1 ml Whole antisera Goat antisera. |
| Uses: | This antibody is useful for ELISA, Western Blot, Immunohistochemistry-Paraffin |
| Localization: | Cell Membrane: attached to the membrane by a GPI anchor. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | Whole antisera |
| Isotype: | IgG |
| Host_Name: | Goat |
| ListPrice: | 325 |
| AppSummary: | ELISA, WB, IHC-P |
| SpeciesSummary: | Hu |
| ALTnames: | Anti-ASCR antibody; Anti-atal familial insomnia antibody; Anti-CD230 antigen antibody; Anti-CJD antibody; Anti-Creutzfeld Jakob disease antibody; Anti-Gerstmann-Strausler-Scheinker syndrome antibody; Anti-GSS antibody; Anti-Major prion protein antibody; Anti-MGC26679 antibody; Anti-Prion related protein antibody; Anti-PRIP antibody; Anti-Prni antibody; Anti-Prnp antibody; Anti-PrP antibody; Anti-PrP27 30 antibody; Anti-PrP33 35C antibody; Anti-PrPC antibody; Anti-PrPSc antibody; Anti-Sinc antibody |
| ProteinTarget: | CD230 |
| PackageSize: | 0.1 ml |
| GeneralRef: | 1. Shinagawa, M. et al. (1986) Immunoreactivity of a synthetic pentadecapeptide corresponding to the N-terminal region of the scrapie prion protein. J. Gen. Virol. 67: 1745-1750. |