| CatalogCode: | NB100-63263 |
| ProductName: | MAdCAM-1 Antibody |
| Product Description: | Mouse Monoclonal anti-MAdCAM-1 (314G8) |
| Clone: | 314G8 |
| Clonality: | Monoclonal |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.5 mg Mouse ascites. |
| Uses: | This antibody is useful for ELISA, Western Blot, flow cytometry / FACS analysis, Immunohistochemistry-Paraffin, Functional |
| Localization: | Membrane; single pass type I membrane protein. |
| Background: | The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM1 (alpha4 beta7), L selectin, and VLA4 (alpha4 beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full length nature of some variants has not been determined. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| ListPrice: | 365 |
| AppSummary: | ELISA, WB, FACS, IHC-P, FC |
| SpeciesSummary: | Hu |
| ALTnames: | Anti-Addressin mucosal antibody; Anti-hMAdCAM 1 antibody; Anti-MACAM1 antibody; Anti-Mucosal addressin cell adhesion molecule 1 antibody; Anti-Mucosal vascular addressin cell adhesion molecule 1 antibody |
| ProteinTarget: | MAdCAM-1 |
| PackageSize: | 0.5 mg |