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| Catalog Code: | NB100-63256 |
| Product Name: | IFN GAMMA Antibody |
| Product Description: | Mouse Monoclonal anti-IFN GAMMA (D9D10) |
| Clone: | D9D10 |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Concentration: | 1.0 mg/ml |
| Immunogen: | Natural human interferon-gamma |
| Specificity: | NB100-63256 recognises both natural and recombinant human interferon gamma, binding only to the dimeric (functional) form |
| Cross Reactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.5 mg Mouse ascites. |
| Uses: | This antibody is useful for ELISA, Western Blot, flow cytometry / FACS analysis |
| Localization: | Secreted |
| Background: | Mammalian Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | Phosphate buffered saline, pH7.2 |
| Application Summary: | ELISA, Western Blot, flow cytometry / FACS analysis |
| Species Summary: | Hu |
| Alternate Names: | Anti-IFG antibody; Anti-IFI antibody; Anti-IFN Gamma antibody; Anti-IFN Immune antibody; Anti-IFNG antibody; Anti-Immune Interferon antibody; Anti-Interferon Gamma Precursor antibody; Anti-Macrophage Activating Factor antibody; Anti-MAF antibody; Anti-T Cell Interferon antibody; Anti-Type II Interferon antibody |
| Package Size: | 0.5 mg |
| Preservative: | 0.09% Sodium Azide |
| General References: | 1. Andersson, U. et al. (1986) Phenotypic characterization of individual interferon gamma producing cells after OKT3 antibody activation. Eur. J. Immunol. 16: 1457-1460. 2. Sandvig, S. et al. (1987) Gamma-interferon is produced by CD3+ and CD3- lymphocytes. Immunol. Rev. 97: 51-65. 3. Andersson, U. et al. (1988) Enumeration of interferon gamma producing cells by flow cytometry: Comparison with fluorescence microscopy. J. Immunol. Methods 112: 139-142. |
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