| CatalogCode: | NB100-63214 |
| ProductName: | PITP ALPHA Antibody |
| Product Description: | Goat Polyclonal anti-PITP ALPHA |
| Clonality: | Polyclonal |
| Immunogen: | Peptide sequence C-VLGIKQGEKHSA corresponding to the C-terminus of PITP alpha. |
| Specificity: | NB100-63214 recognises an epitope within the C-terminal (CT) region of human phosphatidylinositol transfer protein (PITP) alpha, a cytosolic protein with a molecular weight of 32kD. PITP alpha binds and transfers single phosphatidylinositol or phosphatidycholine molecules between membranes. Accumulating evidence has also suggested that PITP proteins play essential functions in choline-phospholipid metabolism, inositol lipid signalling and vesicular membrane traffic. PITP alpha is expressed in a wide range of tissues, and is found in both unicellular and multicellular eukaryotes but not bacteria. |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.1 mg Affinity purified Goat antisera. |
| Uses: | This antibody is useful for ELISA, Western Blot |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | Affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | TRIS buffered saline, pH7.3, 0.5% Bovine Serum Albumin |
| ListPrice: | 340 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | Anti-PITPN antibody |
| ProteinTarget: | PITP ALPHA (C-TERMINAL) |
| PackageSize: | 0.1 mg |
| GeneralRef: | 1. Tremblay, J.M. et al. (2005) Mechanism of interaction of PITPalpha with membranes: conformational changes in the C-terminus associated with membrane binding. Arch. Biochem. Biophys. 444:112-120. 2. van Tiel, C.M. et al. (2002) The structure of phosphatidylinositol transfer protein alpha reveals sites for phospholipid binding and membrane association with major implications for its function. FEBS Lett. 531:69-73. |
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