| CatalogCode: | NB100-63169 |
| ProductName: | HEAT SHOCK PROTEIN 90 ALPHA Antibody |
| Product Description: | Rabbit Polyclonal anti-HEAT SHOCK PROTEIN 90 ALPHA |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide corresponding to amino acids 289-300 of human heat shock protein 90 alpha. |
| Specificity: | NB100-63169 detects human heat shock protein 90 alpha (HSP90a), one of two HSP90 isoforms together with HSP90b. These isoforms are encoded by different genes and under normal conditions assist the folding of newly synthesised proteins, and are also important in cellular processes such as hormone signalling and cell cycle control. In response to mutation or environmental stress, HSP90 expression is upregulated as part of the heat shock response, and function to maintain newly destabilised proteins in a folding competent state. HSP90 can also affect the epigenetic state at specific loci, leading to phenotype modulation.Induction of HSP90a by c-Myc may control the activity of multiple signal pathways involved in cellular transformation. |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.05 mg Affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for ELISA, Western Blot |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | Affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Phosphate buffered saline, pH7.2 |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | Anti-HSP90a antibody |
| ProteinTarget: | HEAT SHOCK PROTEIN 90 ALPHA |
| PackageSize: | 0.05 mg |
| GeneralRef: | 1. Teng, S.C. et al. (2004) Direct activation of HSP90A transcription by c-Myc contributes to c-Myc-induced transformation. J. Biol. Chem. 279: 14649-14655. |