| request information: | |
| Catalog Code: | NB100-63150 |
| Product Name: | ERK1 Antibody |
| Product Description: | Goat Polyclonal anti-ERK1 |
| Clonality: | Polyclonal |
| ListPrice: | 360 |
| Concentration: | 0.5mg/ml |
| Immunogen: | Peptide with sequence C-GGEPRRTEGVGP from the N-terminal of ERK 1 . |
| Specificity: | NB100-63150 detects an epitope within the N-terminal (NT) of extracellular signal-regulated kinase 1 (ERK1). ERK1 is a 45kD protein involved in the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. ERK1 is a member of the MAP kinase (MAPK) family, and is activated by MAP/ERK kinase 1 (MEK1) and MEK2. ERK1 and ERK2, are emerging as important regulators of neuronal responses to both functional and pathologic stimuli. A number of recent studies in models of cerebral ischemia, brain trauma and neurodegenerative diseases implicate a detrimental role for ERK1/2 signalling during oxidative neuronal injury. |
| Cross Reactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.1 mg Affinity purified Goat antisera. |
| Uses: | This antibody is useful for ELISA, Western Blot |
| Localization: | Cytoplasmic |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | Affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu |
| Alternate Names: | Anti-ERK 1 antibody; Anti-ERK antibody; Anti-ERK1 antibody; Anti-ERT 2 antibody; Anti-ERT2 antibody; Anti-Extracellular Signal Regulated Kinase 1 antibody; Anti-Extracellular signal related kinase 1 antibody; Anti-HGNC6877 antibody; Anti-HS44KDAP antibody; Anti-HUMKER1A antibody; Anti-Insulin Stimulated MAP2 Kinase antibody; Anti-MAP kinase 1 antibody; Anti-MAP Kinase antibody; Anti-MAPK 1 antibody; Anti-MAPK 3 antibody; Anti-MAPK antibody; Anti-MAPK1 antibody; Anti-MAPK3 antibody; Anti-MGC20180 antibody; Anti-Microtubule Associated Protein 2 Kinase antibody; Anti-Mitogen Activated Protein Kinase 3 antibody; Anti-p44 ERK1 antibody; Anti-p44 MAPK antibody; Anti-P44ERK1 antibody; Anti-P44MAPK antibody; Anti-PRKM 3 antibody; Anti-PRKM3 antibody; Anti-Protein Kinase Mitogen Activated 3 antibody |
| Package Size: | 0.1 mg |
| Preservative: | Sodium Azide |
| General References: | 1. Nishimoto, S. and Nishida, E. (2006) MAPK signalling: ERK5 versus ERK1/2. EMBO Rep. 7: 782-6. 2. Chu, C.T. et al. (2004) The dark side of ERK1/2. Eur. J. Biochem. 271: 2060-2066. |
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