| request information: |
|
| Catalog Code: | NB100-63137 |
| Product Name: | CRMP2 Antibody |
| Product Description: | Goat Polyclonal anti-CRMP2 |
| Clonality: | Polyclonal |
| ListPrice: | 325 |
| Immunogen: | Synthetic peptide corresponding amino acid sequence 543-557 of human CRMP2. |
| Specificity: | NB100-63137 recognises collapsin response mediator protein 2 (CRMP2), a ubiquitously expressed, 62 kDa member of the dehydropyrimidinase family. It is involved in axon formation and outgrowth by transporting to axons, the actin cytoskeleton regulating; Rac1-associated protein 1 (Sra-1)/WASP family verprolin-homologous protein 1 (WAVE1) complex. CRMP2 also regulates axon formation and branching by binding tubulin heterodimers thereby enhancing microtubule polymerisation. Through its interaction with ROKalpha, CRMP2 is also thought to play a role in RhoA-dependent signalling. CRMP2 is associated with mesial temporal lobe epilepsy and schizophrenia. |
| Cross Reactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.1 ml Whole antisera Goat antisera. |
| Uses: | This antibody is useful for ELISA, Western Blot |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | Whole antisera |
| Isotype: | IgG |
| Host Name: | Goat |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu |
| Package Size: | 0.1 ml |
| Preservative: | Sodium Azide |
| General References: | 1. Kawano, Y. et al. (2005) CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formation. Mol. Cell. Biol. 25:9920-9935. |
order or
more information: | company product webpage |