| CatalogCode: | NB100-63007 |
| ProductName: | IFN GAMMA Antibody |
| Product Description: | Rat Monoclonal anti-IFN GAMMA (XMG1.2) |
| Clone: | XMG1.2 |
| Clonality: | Monoclonal |
| Specificity: | Recognises murine IFN gamma. This reagent may be used for the detection of intracellular IFN gamma using flow cytometric techniques. |
| CrossReactivity: | Mouse. Not yet tested in other species. |
| Packaging: | 0.25 mg Rat ascites. |
| Uses: | This antibody is useful for ELISA, flow cytometry / FACS analysis |
| Localization: | Secreted |
| Background: | Mammalian Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Isotype: | IgG1 |
| Host_Name: | Rat |
| Buffer: | Phosphate buffered saline |
| ListPrice: | 285 |
| AppSummary: | ELISA, FACS |
| SpeciesSummary: | Mu |
| ALTnames: | Anti-IFNG antibody; Anti-IFG antibody; Anti-IFI antibody; Anti-IFN Gamma antibody; Anti-IFN Immune antibody; Anti-Immune Interferon antibody; Anti-Interferon Gamma Precursor antibody; Anti-Macrophage Activating Factor antibody; Anti-MAF antibody; Anti-T Cell Interferon antibody; Anti-Type II Interferon antibody |
| ProteinTarget: | IFN GAMMA |
| PackageSize: | 0.25 mg |
| GeneralRef: | 1. Holz, A. et al. (2001) Constitutive beta cell expression of IL-12 does not perturb self-tolerance but intensifies established autoimmune diabetes. J. Clin. Invest. 108: 1749 - 1758. |