| CatalogCode: | NB100-63005 |
| ProductName: | IFN GAMMA Antibody |
| Product Description: | Mouse Monoclonal anti-IFN GAMMA (A35) |
| Clone: | A35 |
| Clonality: | Monoclonal |
| Specificity: | Specific for human interferon gamma (IFN gamma). IFN gamma is a regulatory cytokine, which is produced by activated natural killer cells and a population of T-lymphocytes. |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.5 mg Mouse ascites. |
| Uses: | This antibody is useful for ELISA, flow cytometry / FACS analysis |
| Background: | Mammalian Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Phosphate buffered saline |
| ListPrice: | 325 |
| AppSummary: | ELISA, FACS |
| SpeciesSummary: | Hu |
| ALTnames: | Anti-INTERFERON GAMMA antibody |
| ProteinTarget: | IFN GAMMA |
| PackageSize: | 0.5 mg |
| GeneralRef: | 1. Abrams, J. et al. (1992) Strategies of anti-cytokine monoclonal antibody development. Immunol. Rev. 127:5-24. 2. Paliard, X. et al. (1988) Simultaneous production of IL-2, IL-4 and IFN-gamma by activated human CD4+ and CD8+ T-cell clones. J. Immunol. 141:849-855. 3. Wakkach, A. et al. (2001) Differentiation of Regulatory T cells 1 is induced by CD2 costimulation. J. Immunol. 167:3107-3113. |
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