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| Catalog Code: | NB100-62953 |
| Product Name: | THYROGLOBULIN Antibody |
| Product Description: | Mouse Monoclonal anti-THYROGLOBULIN (BGN/6D7) |
| Clone: | BGN/6D7 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Purified human thyroglobulin. |
| Specificity: | Recognises Thyroglobulin (Tg), reacting with circulating Tg (Tg/T4 complex). |
| Cross Reactivity: | Human. Not yet tested in other species. |
| Packaging: | 1 mg protein G purified Mouse ascites. |
| Uses: | This antibody is useful for ELISA |
| Localization: | Secreted |
| Background: | Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG2b |
| Host Name: | Mouse |
| Buffer: | Phosphate buffered saline, pH 7.2 |
| Application Summary: | ELISA |
| Species Summary: | Hu |
| Alternate Names: | Anti-AITD 3 antibody; Anti-AITD3 antibody; Anti-hTG antibody; Anti-TG antibody; Anti-Tgn antibody |
| Package Size: | 1 mg |
| Preservative: | 0.09% Sodium Azide |
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