| CatalogCode: | NB100-62688 |
| ProductName: | IL-6 Antibody |
| Product Description: | Mouse Monoclonal anti-IL-6 (BGN/2H6) |
| Clone: | BGN/2H6 |
| Clonality: | Monoclonal |
| Immunogen: | Native |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.2 mg of Fractionation or chromatography Purified IgG |
| Uses: | This antibody is useful for ELISA |
| Localization: | Secreted |
| Background: | Interleukin 6 (IL6) is a multifunctional 24 kDa protein originally discovered in the medium of RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNF alpha, NGF, IL17 and downregulated by glucocorticoids IL4, TGF beta. IL6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL6 has also been implicated in regulating adipose mass. IL6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. It acts upon a variety of cells including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. In addition, IL6 appears to interact with IL2 in the proliferation of T lymphocytes. IL6 potentiates the proliferative effect of IL3 on multipotential hematopoietic progenitors. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | PBS buffer, pH 7.2 |
| ListPrice: | 295 |
| AppSummary: | ELISA |
| SpeciesSummary: | Hu |
| ALTnames: | anti-B cell stimulatory factor 2 antibody, anti-BSF 2 antibody, anti-BSF2 antibody, anti-CDF antibody, anti-CTL differentiation factor antibody, anti-Cytotoxic T cell differentiation factor antibody, anti-Hepatocyte stimulating factor antibody, anti-HGF antibody, anti-HPGF antibody, anti-HSF antibody, anti-Hybridoma growth factor antibody, anti-Hybridoma plasmacytoma growth factor antibody, anti-IFNB2 antibody, anti-IL 6 antibody, anti-IL6 protein antibody, anti-Interferon beta 2 antibody, anti-Interleukin 6 antibody, anti-Interleukin6 antibody |
| ProteinTarget: | IL-6 |
| PackageSize: | 0.2 mg |
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