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| Catalog Code: | NB100-62638 |
| Product Name: | hCG BETA Antibody |
| Product Description: | Mouse Monoclonal anti-hCG BETA (152 (2F4/3)) |
| Clone: | 152 (2F4/3) |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 5.0 mg/ml |
| Immunogen: | hCG, beta subunit |
| Specificity: | NB100-62638 is specific for the beta subunit of human chorionic gonadotrophin (hCG) and recognizes both the free subunit and the whole molecule. Negligible reactivity has been observed with hLH, hTSH and hFSH.HCG is a 39.5 kDa peptide hormone that is composed of one alpha and one beta subunit. The beta subunit, a 145 amino acid sequence, is unique to hCG and specific tests for it are not subject to hormonal cross reactivity. hCG is secreted by placental syncytiotrophoblasts and stimulates the ovaries to produce steroids that are essential to pregnancy. |
| Cross Reactivity: | Human. Not yet tested in other species. |
| Packaging: | 1 mg Affinity purified Mouse ascites. |
| Uses: | This antibody is useful for ELISA |
| Localization: | Cytoplasmic and Secreted |
| Background: | Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | Affinity purified |
| Isotype: | IgG |
| Host Name: | Mouse |
| Buffer: | Phosphate buffered saline pH7.4 |
| Application Summary: | ELISA |
| Species Summary: | Hu |
| Alternate Names: | anti-CG beta antibody, anti-CGB 3 antibody, anti-CGB 5 antibody, anti-CGB 7 antibody, anti-CGB antibody, anti-CGB3 antibody, anti-CGB5 antibody, anti-CGB7 antibody, anti-Choriogonadotropin subunit beta antibody, anti-Chorionic gonadotropin beta 3 subunit precursor antibody, anti-Chorionic gonadotropin beta chain antibody, anti-Chorionic gonadotropin beta polypeptide antibody, anti-Chorionic gonadotropin beta subunit antibody, anti-hCGB antibody |
| Package Size: | 1 mg |
| Preservative: | 0.09% Sodium Azide (NaN3) |
| Notes Main: | Affinity: 2 x 10^10 |
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