| CatalogCode: | NB100-62637 |
| ProductName: | hCG ALPHA Antibody |
| Product Description: | Mouse Monoclonal anti-hCG ALPHA (176 (2F7)) |
| Clone: | 176 (2F7) |
| Clonality: | Monoclonal |
| Immunogen: | Human hCG alpha subunit |
| Specificity: | NB100-62637 is specific for the alpha subunit of human chorionic gonadotrophin (CG), luteinizing hormone (LH) and follicle stimulating hormone (FSH). It is also thought to react with alpha subunits of thyroid stimulating hormone (TSH).Human CG is a 39.5 kDa peptide hormone that is composed of one alpha and one beta subunit. The alpha subunit is identical to that of LH, TSH and FSH. CG is secreted by placental syncytiotrophoblasts and stimulates the ovaries to produce steroids that are essential to pregnancy. This antibody may be used in combination with clone 2D8 (0200-0094) in sandwich ELISA assays. |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 1 mg Affinity purified Mouse ascites. |
| Uses: | This antibody is useful for ELISA |
| Localization: | Secreted |
| Background: | Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | Affinity purified |
| Isotype: | IgG |
| Host_Name: | Mouse |
| Buffer: | Phosphate buffered saline pH7.4 |
| ListPrice: | 285 |
| AppSummary: | ELISA |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Anterior pituitary glycoprotein hormones common subunit alpha antibody, anti-CG alpha antibody, anti-CGA antibody, anti-Choriogonadotropin Alpha Chain antibody, anti-Chorionic Gonadotrophin Alpha Subunit antibody, anti-Chorionic gonadotropin alpha polypeptide antibody, anti-Follicle Stimulating Hormone Alpha Chain antibody, anti-Follitropin Alpha Chain antibody, anti-FSH Alpha antibody, anti-FSHA antibody, anti-Glycoprotein hormones alpha chain antibody, anti-Glycoprotein Hormones Alpha Polypeptide antibody, anti-GPH Alpha antibody, anti-GPHa antibody, anti-GPHA1 antibody, anti-HCG antibody, anti-LHA antibody, anti-LSH alpha antibody, anti-Luteinizing Hormone Alpha Chain antibody, anti-Lutropin Alpha Chain antibody, anti-Thyroid Stimulating Hormone Alpha Chain antibody, anti-Thyrotropin Alpha Chain antibody, anti-TSH Alpha antibody, anti-TSHA antibodying factor antibody, anti-Lysyl-bradykinin antibody |
| ProteinTarget: | hCG ALPHA |
| PackageSize: | 1 mg |
| NotesMain: | Affinity: 4 x 10^10 L/mol. |
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