| CatalogCode: | NB100-62615 |
| ProductName: | GRANZYME A Antibody |
| Product Description: | Rabbit Polyclonal anti-GRANZYME A |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide corresponding to the amino acids 15 - 25 of the native molecule conjugated to Keyhole Limpet Haemocyanin. |
| Epitope: | V-L-L-S-L-D-R-K-T-I-C |
| Specificity: | Pep-BSA 100% pep 80-100% |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 1 ml of Ammonium Sulphate fractionation Purified IgG |
| Uses: | This antibody is useful for ELISA |
| Localization: | Secreted protein; cytoplasmic granule. |
| Background: | Granzyme A is the most abundant of the proteases occurring in CTL granules. It is homologous to other serine esterases, including other granyzmes, mast cell proteases, and neutrophil cathepsins. Granzyme A is unique among granzymes in that it is a disulfide linked homodimer. Granzyme B is thought to be a rapidly acting apoptotic enzyme, while Granzyme A is thought to be slow acting. Granzyme A is a 28 kD protein. Granzyme A deficient mice are indistinguishable from normal animals in their response to infection. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | PBS buffer, pH 7.2 |
| ListPrice: | 295 |
| AppSummary: | ELISA |
| SpeciesSummary: | Hu |
| ALTnames: | anti-CTL tryptase antibody, anti-CTLA3 antibody, anti-Cytolytic t cell and natural killer cell specific trypsin like serine protease antibody, anti-Cytotoxic T lymphocyte associated serine esterase 3 antibody, anti-Cytotoxic T lymphocyte proteinase 1 antibody, anti-Fragmentin 1 antibody, anti-Granzyme 1 cytotoxic T lymphocyte associated serine esterase 3 antibody, anti-Granzyme A precursor antibody, anti-GZMA antibody, anti-H factor antibody, anti-Hanukah factor serine protease antibody, anti-HFSP antibody, anti-TSP1 antibody |
| ProteinTarget: | GRANZYME A |
| PackageSize: | 1 ml |
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