| CatalogCode: | NB100-62591 |
| ProductName: | GELSOLIN Antibody |
| Product Description: | Sheep Polyclonal anti-GELSOLIN |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide corresponding to the amino acids 11 - 24 of the native molecule conjugated to Keyhole limpet Haemocyanin. |
| Epitope: | G-A-P-Q-G-R-V-P-E-A-R-P-N-S |
| Specificity: | Reactive with native bovine serum gelsolin in a simple ELISA. The N-terminal human plasma form sequence used for this antibody is in an area not present in the cytoplasmic form of the molecule. |
| CrossReactivity: | Reacts with: Bovine |
| Packaging: | 1 ml of Ammonium Sulphate fractionation Purified IgG |
| Uses: | This antibody is useful for ELISA |
| Background: | Gelsolin is a calcium dependent actin binding protein. It is a potent modulator of actin filament length and gelation. Gelsolin has been shown to exist in at least two variant forms, cytoplasmic gelsolin and plasma gelsolin. Plasma gelsolin has also been called actin depolymerizing factor (ADF) or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25 amino acid residue extension at the NH2 terminus in the human plasma gelsolin which appears to account for the difference in relative molecular weights. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host_Name: | Sheep |
| Buffer: | Phosphate buffered saline, pH7.2 |
| ListPrice: | 285 |
| AppSummary: | ELISA |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Actin depolymerizing factor antibody, anti-ADF antibody, anti-AGEL antibody, anti-Amyloidosis Finnish type antibody, anti-Brevin antibody, anti-DKFZp313L0718 antibody, anti-GSN antibody |
| ProteinTarget: | GELSOLIN (PLASMA) |
| PackageSize: | 1 ml |