| CatalogCode: | NB100-62586 |
| ProductName: | GAD 67kDa Antibody |
| Product Description: | Rabbit Polyclonal anti-GAD 67kDa |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide corresponding to the amino acids 16 - 28 of the native molecule conjugated to Keyhole limpet Haemocyanin. |
| Epitope: | G-A-D-P-N-T-T-N-L-R-P-T-T-{C} |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 1 ml of Ammonium Sulphate fractionation Purified IgG |
| Uses: | This antibody is useful for ELISA |
| Background: | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | PBS buffer, pH 7.2 |
| ListPrice: | 295 |
| AppSummary: | ELISA |
| SpeciesSummary: | Hu |
| ALTnames: | anti-GLUTAMATE DECARBOXYLASE antibody |
| ProteinTarget: | GAD 67kDa |
| PackageSize: | 1 ml |