| CatalogCode: | NB100-62170 |
| ProductName: | ALPHA 2 MACROGLOBULIN Antibody |
| Product Description: | Sheep Polyclonal anti-ALPHA 2 MACROGLOBULIN |
| Clonality: | Polyclonal |
| Immunogen: | Human alpha 2 -macroglobulin purified from plasma |
| Specificity: | NB100-62170 recognises alpha 2-macroglobulin, a tetrameric glycoprotein of 720kD which functions as a proteinase inhibitor. |
| CrossReactivity: | Reacts with: Bovine, Horse, Guinea Pig, Pig, Dog, Cat, Rabbit |
| Packaging: | 1 ml of ion exchange chromatography Purified IgG |
| Uses: | This antibody is useful for Immunohistochemistry-Frozen & Immunodiffusion |
| Localization: | Secreted |
| Background: | Alpha 2 macroglobulin is a serum protein which is mainly synthesised in the liver. It functions as a broad range irreversible proteinase inhibitor that forms a "trap" around most proteases. Alpha 2 macroglobulin is a tetrameric molecule, and with a molecular weight of 720 kDa, it so large a molecule that it tends to remain intravascular. Following conformational change the proteinase is deposited within a central cavity where it is still active but prevented from further contact with its substrate. Removal of the complex is mediated by the generation of recognition sites which react with receptors on a variety of cells including macrophages and liver cells. Alpha 2 macroglobulin is localized on the surface of peripheral blood lymphocytes. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Isotype: | IgG |
| Host_Name: | Sheep |
| Buffer: | Glycine buffered saline pH7.4 |
| ListPrice: | 285 |
| AppSummary: | IHC-Fr, ID |
| SpeciesSummary: | Hu |
| ALTnames: | anti-A2M antibody, anti-Alpha 2 M antibody, anti-Alpha 2M antibody, anti-CPAMD5 antibody, anti-DKFZp779B086 antibody, anti-FWP007 antibody, anti-S863 7 antibody |
| ProteinTarget: | ALPHA 2 MACROGLOBULIN |
| PackageSize: | 1 ml |
order or
more information: | company product webpage |
| request information: |
|