| CatalogCode: | NB100-62147 |
| ProductName: | CD56 Antibody |
| Product Description: | Mouse Monoclonal anti-CD56 (ERIC-1) |
| Clone: | ERIC-1 |
| Clonality: | Monoclonal |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.2 mg of Purified IgG |
| Uses: | This antibody is useful for Immunohistochemistry-Frozen, ELISA, Immunoblotting |
| Background: | CD56, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig) like domains. The extracellular part of CD56 consists of five of these Ig domains and two fibronectin type III homology regions. CD56 is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of CD56. Through its extracellular region, CD56 mediates homophilic interactions. In addition, CD56 can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasm such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | Affinity Purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| ListPrice: | 295 |
| AppSummary: | IHC-Fr, ELISA, IB |
| SpeciesSummary: | Hu |
| ProteinTarget: | CD56 |
| PackageSize: | 0.2 mg |
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