| CatalogCode: | NB100-62130 |
| ProductName: | H-FABP Antibody |
| Product Description: | Mouse Monoclonal anti-H-FABP (9F3) |
| Clone: | 9F3 |
| Clonality: | Monoclonal |
| Immunogen: | Human heart FABP (H-FABP) |
| Specificity: | NB100-62130 detects human H-FABP, also known as heart type fatty-acid binding protein, and FABP3. H-FABP belongs to the FABP family, and is a 14kDa cytosolic non-enzymatic protein involved in the uptake, transport and metabolism of fatty acids. H-FABP also has a role in cell proliferation and is a candidate tumour suppressor gene in breast cancer.H-FABP was initially purified from the heart muscle, but has since been found to have a widespread tissue distribution, with highest concentration in cardiac and skeletal muscle.H-FABP has been implicated in neurodegenerative disorders, including Down syndrome and Alzheimer's disease, and is a specific and sensitive biomarker for acute myocardial infarctions. |
| CrossReactivity: | Human. Not yet tested in other species. |
| Packaging: | 0.2 mg protein A purified Mouse ascites. |
| Uses: | This antibody is useful for ELISA, Immunoassay |
| Localization: | Cytoplasmic |
| Background: | Fatty Acid Binding Protein (FABP) is a small cytosolic protein responsible for the transport and deposition of fatty acids inside the cell. Several different isoforms of FABP are expressed in different tissue types. Cardiac isoform of FABP (cFABP) is expressed mainly in cardiac muscle tissue and in significantly lower concentration in skeletal muscles. This antibody can be used to detect ischemia areas of human heart. It is also useful as marker for brain damage. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purity: | protein A purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Phosphate buffered saline pH7.4 |
| ListPrice: | 285 |
| AppSummary: | ELISA, IA |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Muscle fatty acid binding protein antibody, anti-422 protein antibody, anti-Cardiac Fatty Acid Binding Protein antibody, anti-FABP 11 antibody, anti-FABP 3 antibody, anti-FABP11 antibody, anti-FABP3 antibody, anti-fatty acid binding protein 11 antibody, anti-Fatty acid binding protein 3 antibody, anti-Fatty acid binding protein 3 muscle and heart antibody, anti-Fatty acid binding protein 3 muscle antibody, anti-Fatty acid binding protein heart antibody, anti-H FABP antibody, anti-Heart type fatty acid binding protein antibody, anti-M FABP antibody, anti-mammary derived growth inhibitor antibody, anti-Mammary-derived growth inhibitor antibody, anti-MDGI antibody, anti-mylein protein P2 homolog antibody, anti-O FABP antibody, anti-P2 adopocyte protein antibody |
| ProteinTarget: | H-FABP |
| PackageSize: | 0.2 mg |
| GeneralRef: | 1. Steinacker, P. et al. (2004) Heart fatty acid binding protein as a potential diagnostic marker for neurodegenerative diseases. Neurosci. Lett. 370: 36-39. 2. Cheon, M.S. et al. (2003) Heart type fatty acid binding protein (H-FABP) is decreased in brains of patients with Down syndrome and Alzheimer's disease. J. Neural. Transm. Suppl. 67: 225-234. 3. Tambara, K. et al. (2004) Pericardial fluid level of heart-type cytoplasmic fatty acid-binding protein (H-FABP) is an indicator of severe myocardial ischemia. Int. J. Cardiol. 93: 281-284. |
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