| Catalog Code: | NB100-61653 |
| Product Type: | Primary Antibody |
| Product Name: | GAB2 Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 9846 |
| Host: | Goat |
| Isotype: | IgG |
| Product Description: | Goat Polyclonal anti-GAB2 |
| Cross Reactivity: | Human. Other species not tested. Expected based upon sequence homology: Mouse, Rat, Dog |
| Species Summary: | Hu |
| Background: | This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for t |
| Alternate Names: | anti-GAB2 antibody, anti-GRB2-associated binding protein 2 antibody, anti-KIAA0571 antibody, anti-Grb2-associated binder 2 antibody |
| Immunogen: | Synthetic peptide, C-QVDKEKTQALQN, representing the internal region (near the C Terminus) of the sequence according to NP_536739.1; NP_036428.1 |
| Epitope: | QVDKEKTQALQN |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris-saline [pH7.3] with 0.5% BSA |
| Preservative: | 0.02% sodium azide |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Approx 80kDa band observed in lysates of cell line K562 (calculated MW of 74.5kDa according to NP_536739.1). Recommended concentration: 0.5-1.5ug/ml. |
| Application Summary: | ELISA, WB |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| General References: | Bentires-Alj M, Gil SG, Chan R, Wang ZC, Wang Y, Imanaka N, Harris LN, Richardson A, Neel BG, Gu H. A role for the scaffolding adapter GAB2 in breast cancer. Nat Med. 2006 Jan;12(1):114-21. Epub 2005 Dec 20. PMID: 16369543 |