| CatalogCode: | NB100-61613 |
| ProductName: | CAD Antibody |
| Product Description: | Rabbit Polyclonal anti-CAD |
| Clonality: | Polyclonal |
| Immunogen: | The epitope recognized by this antibody maps to a region between residue 1650 and 1700 of human carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase using the numbering given in entry NP_004332.2 (GeneID 790). |
| CrossReactivity: | Human, Mouse. Other species not tested. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for Western Blot. It is not recommended for immunoprecipitation. |
| Background: | The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Tris-buffered Saline containing 0.1% BSA |
| ListPrice: | 325 |
| AppSummary: | WB |
| SpeciesSummary: | Hu, Mu |
| ALTnames: | anti-CAD antibody, anti-carbamoyl-phosphate synthetase 2 antibody, anti-aspartate transcarbamylase antibody, anti-and dihydroorotase. antibody |
| ProteinTarget: | CAD |
| PackageSize: | 0.02 mg |
| Gene_Id: | 790 |
| Ref_Sqnce: | NP_004332.2 |
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