| CatalogCode: | NB100-60954 |
| ProductName: | G6PD Antibody |
| Product Description: | Goat Polyclonal anti-G6PD (internal) |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide, C-STNSDDVRDEKVK, representing the internal region of the sequence according to NP_000393.4 ; NP_001035810.1 |
| Epitope: | STNSDDVRDEKVK |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 55-60kDa double band observed in Human Testis, Thyroid and Tonsil lysates (calculated MW of 62.5kDa according to NP_000393.4 and 59.3kDa accordiong to NP_001035810.1). Recommended concentration: 0.03-0.1ug/ml. |
| Control: | Human Testis lysate |
| Background: | This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline [pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-G6PD antibody; anti-glucose-6-phosphate dehydrogenase antibody; anti-G6PD1 antibody; anti-glucose-6-phosphate 1-dehydrogenase antibody; anti-glucose-6-phosphate dehydrogenase antibody; anti-G6PD antibody |
| ProteinTarget: | G6PD |
| PackageSize: | 0.1 mg |
| Homology: | Human, Mouse, Rat, Dog |
| GeneralRef: | Guindo A, Fairhurst RM, Doumbo OK, Wellems TE, Diallo DA. X-Linked G6PD Deficiency Protects Hemizygous Males but Not Heterozygous Females against Severe Malaria. PLoS Med. 2007 Mar 13;4(3):e66 [Epub ahead of print] PMID: 17355169 |
| NotesMain: | Non Human Gene IDs: 14381 (mouse); 24377 (rat); This antibody is expected to recognise both reported isoforms (NP_000393.4 and NP_001035810.1). |
| Gene_Id: | 2539 |
| Gene_Symbol: | G6PD |
| Ref_Sqnce: | NP_000393.4 ; NP_001035810.1 |
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