| CatalogCode: | NB100-60679 |
| ProductName: | ERCC4 Antibody |
| Product Description: | Rabbit Polyclonal anti-XPF/ERCC4 |
| Clonality: | Polyclonal |
| Immunogen: | The epitope recognized by this antibody maps to a region between residue 855 and 905 of human xeroderma pigmentosum, complementation group F using the numbering given in entry AAB07689.1 (GeneID 2072). |
| CrossReactivity: | Human. Other species not yet tested. |
| Packaging: | 0.02 mg of affinity purified antibody. |
| Uses: | This antibody is useful for Western Blot and Immunoprecipitation. |
| Background: | XPF/ERCC4 is suggested to play a role in the repair of DNA double-strand breaks (DSB), homologous recombination, and gene conversion via single-strand annealing (SSA). XPF/ERCC4 is an endonuclease that incises 5-prime DNA. Defects in XPF/ERCC4 cause xeroderma pigmentosum VI (XP6) an autosomal recessive disease characterized by hypersensitivity to sunlight and a predisposition to skin cancer as well as neurological abnormalities. Defects in XPF/ERCC4 are also responsible for XFE progeroid syndrome, a syndrome characterized by dwarfism, cachexia, and microcephaly. Alternate names for XPF/ERCC4 include DNA repair endonuclease XPF, DNA excision repair protein ERCC-4, DNA-repair protein complementing XP-F cells, xeroderma pigmentosum group F-complementing protein, ERCC11, and RAD1. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-buffered saline, 0.1% BSA |
| ListPrice: | 325 |
| AppSummary: | WB, IP |
| SpeciesSummary: | Hu |
| ALTnames: | anti-XPF antibody, anti-xeroderma pigmentosum antibody, anti-complementation group F antibody, anti-ERCC4 antibody, anti-ERCC-4 antibody, anti-excision repair cross-complementing rodent repair deficiency antibody, anti-complementation group 4 antibody, anti-RAD1 antibody |
| ProteinTarget: | ERCC4 |
| PackageSize: | 0.02 mg |
| Gene_Id: | 2072 |
| Omim_ID: | NB100-74611 |
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