| CatalogCode: | NB100-60640 |
| ProductName: | TAF6 Antibody |
| Product Description: | Rabbit Polyclonal anti-TAF6 |
| Clonality: | Polyclonal |
| Immunogen: | The epitope recognized by this antibody maps to a region between residue 627 and 677 of human TBP-associated factor 6 using the numbering given in entry NP_005632.1 (GeneID 6878). |
| CrossReactivity: | Human. Other species not yet tested. |
| Packaging: | 0.02 mg of affinity purified antibody. |
| Uses: | This antibody is useful for Western Blot and Immunoprecipitation. |
| Background: | Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Four isoforms have been identified but complete transcripts have been determined for only three isoforms. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-buffered saline, 0.1% BSA |
| ListPrice: | 325 |
| AppSummary: | WB, IP |
| SpeciesSummary: | Hu |
| ALTnames: | anti-TAF6 antibody, anti-TAF-6 antibody, anti-TBP-associated factor 6 antibody, anti-TAF2E antibody, anti-TATA box binding protein (TBP)-associated factor antibody, anti-RNA polymerase II antibody, anti-E antibody, anti-TAFII70 antibody, anti-transcription initiation factor TFIID 70 kD subunit antibody, anti-TAFII85 antibody, anti-TATA box binding protein (TBP)-associated factor antibody, anti-RNA polymerase II antibody |
| ProteinTarget: | TAF6 |
| PackageSize: | 0.02 mg |
| Gene_Id: | 6878 |
| Omim_ID: | NB100-60639 |
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