| CatalogCode: | NB100-58827 |
| ProductName: | SMRT Antibody |
| Product Description: | Rabbit Polyclonal anti-SMRT |
| Clonality: | Polyclonal |
| Immunogen: | Antibody was affinity purified using an epitope specific to SMRT immobilized on solid support.The epitope recognized by this antibody maps to a region between residue 1925 and 1975 of human silencing mediator of retinoic acid and thyroid hormone receptor alpha using the numbering given in entry AAD20946.1 (GeneID 9612). Antibody concentration was determined by extinction coefficient: absorbance at 280 |
| CrossReactivity: | Human. No other species have been tested. |
| Packaging: | 0.1 mg of antigen affinity purified antibody. |
| Uses: | Western Blot - Not recommended. Immunoprecipitation - 2 to 5 mcg/mg lysate. Immunohisto-/cytochemistry - Not tested. |
| Background: | Nuclear hormone receptors are transcription factors regulated by ligand binding. In the absence of ligand there is a physical interaction between the nuclear receptors that do not interact with Hsp90 and a family of corepressors which includes SMRT. SMRT helps target histone deacetylases and other components of a multiprotein repressor complex to the specific target promoter to silence gene transcription. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-citrate/phosphate buffer, pH 7 to 8 |
| ListPrice: | 325 |
| AppSummary: | IP |
| SpeciesSummary: | Hu |
| ALTnames: | anti-SMRT antibody, anti-SMRTE antibody, anti-SMRTE-tau antibody, anti-silencing mediator for retinoid and thyroid hormone receptors antibody, anti-NCoR2 antibody, anti-NCoR-2 antibody, anti-nuclear receptor co-repressor 2 antibody, anti-TRAC1 antibody, anti-TRAC-1 antibody, anti-Thyroid- antibody, anti-retinoic-acid-receptor-associated corepressor antibody T3 receptor-associating factor antibody, anti-TNRC14 antibody, anti-SMAP270 antibody |
| ProteinTarget: | SMRT |
| PackageSize: | 0.1 mg |
| Gene_Id: | 9612 |
| Gene_Symbol: | NCOR2 |
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