| CatalogCode: | NB100-58753 |
| ProductName: | Platelet-Derived Growth Factor Receptor Beta (PDGFRB) Antibody |
| Product Description: | Rabbit Polyclonal anti-Platelet-Derived Growth Factor Receptor Beta (PDGFRB) |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide - KLH conjugated |
| Epitope: | Extracellular domain of human protein |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.05 mg of antigen affinity purified antisera |
| Uses: | Immunohistochemistry (Paraffin-embedded sections): Recommended starting dilution 20 µg/ml |
| Control: | Kidney, Renal Tubular Epithelium in Cortex |
| Background: | This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Phosphate buffered saline |
| ListPrice: | 350 |
| AppSummary: | IHC-P |
| SpeciesSummary: | Hu |
| ALTnames: | anti-CD140B antibody, anti-EC 2.7.10.1 antibody, anti-JTK12 antibody, anti-PDGF-R-BETA antibody, anti-PDGFR antibody, anti-PDGFR1 antibody, anti-PDGFRB antibody |
| ProteinTarget: | Platelet-Derived Growth Factor Receptor Beta (PDGFRB) |
| PackageSize: | 0.05 mg |
| Gene_Id: | 5159 |
| Gene_Symbol: | PDGFRB |