| Catalog Code: | NB100-573 |
| Product Type: | Primary Antibody |
| Product Name: | BUB-3 Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 9184 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-BUB-3 |
| Cross Reactivity: | Human. Other species not tested. Reactivity with mouse and X. laevis BUB3 is likely owing to conservation of sequence between these orthologs and human BUB3 at the site to which the epitope maps. |
| Species Summary: | Hu |
| Background: | The spindle checkpoint ensures the fidelity of chromosome segregation in mitosis and meiosis. In response to defects in the mitotic apparatus, it blocks the activity of the anaphase-promoting complex, a large ubiquitin ligase required for chromosome segre |
| Alternate Names: | anti-BUB3 antibody, anti-BUB-3 antibody, anti-BUB3L antibody, anti-Budding uninhibited by benzimidazoles 3 antibody, anti- HGNC:1151 antibody |
| Immunogen: | A synthetic peptide which maps to a region between residues 275 and 325 of human BUB3 using the numbering given in Swiss-Prot entry O43684 (GeneID 9184). |
| Specificity: | NB 100-573 is specific for human BUB3 protein. |
| Packaging: | 0.1 ml of affinity purified rabbit sera in a Tris-citrate/phosphate (pH 7-8) buffer with 0.1% sodium azide. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | Optimal working dilutions should be determined experimentally by the investigator. Prepare working dilution immediately before use. Suggested starting dilutions are as follows. Western Blot: 1:5,000 - 1:15,000 Immunoprecipitation: not tested Histo/Cyt |
| Application Summary: | WB |
| Notes Main: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |