| CatalogCode: | NB100-57077 |
| ProductName: | RAD9A Antibody |
| Product Description: | Goat Polyclonal anti-RAD9A |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide, C-QGPSPVLAEDSEGE, representing the C Terminus of the human protein according to NP_004575.1 |
| Epitope: | QGPSPVLAEDSEGE |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:32,000. Approx 70kDa band observed in lysates of cell lines A431 and Daudi (calculated MW of 42.5kDa according to NP_004575.1). The observed molecular weight corresponds to earlier findings in literature (Volkmer et al, J Biol Chem. 1999 Jan 8;274(2):567-70.; PMID: 9872989). Recommended concentration: 0.3-1ug/ml. |
| Background: | This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline [ pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-RAD9A antibody, anti-RAD9A, anti-RAD9A antibody, anti-RAD9 homolog A (S. pombe)antibody, anti-RAD9antibody, anti-RAD9 (S. pombe) homolog antibody, anti-RAD9 homolog antibody, anti-RAD9 homolog (S. pombe) antibody, anti-cell cycle checkpoint control proteinantibody, anti-RAD9A, anti-RAD9 homolog A (S. pombe), anti-RAD9, anti-RAD9 (S. pombe) homolog, anti-RAD9 homolog, anti-RAD9 homolog (S. pombe), anti-cell cycle checkpoint control proteinantibody, antibody |
| ProteinTarget: | RAD9A |
| PackageSize: | 0.1 mg |
| Homology: | Human, Mouse, Dog |
| GeneralRef: | Brandt PD, Helt CE, Keng PC, Bambara RA. The Rad9 protein enhances survival and promotes DNA repair following exposure to ionizing radiation. Biochem Biophys Res Commun. 2006 Aug 18;347(1):232-7. Epub 2006 Jun 21. PMID: 16814252 |
| NotesMain: | Other Gene ID: 19367 (mouse); |
| Gene_Id: | 5883 |
| Omim_ID: | PAB0581 |
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