| CatalogCode: | NB100-569 |
| ProductName: | MAD-1 Antibody |
| Product Description: | Rabbit Polyclonal anti-MAD-1 |
| Clonality: | Polyclonal |
| Immunogen: | A synthetic peptide which maps to a region between residues 1 and 50 of human Mitotic arrest deficient-like 1 using the numbering given in Swiss-Prot entry Q9Y6D9 (GeneID 8379). |
| Specificity: | NB 100-569 is specific for human MAD1 protein. |
| CrossReactivity: | Human. Other species not tested. Reactivity with mouse MAD1 is likely owing to conservation of sequence between this ortholog and human MAD1 at the site to which the epitope maps. |
| Packaging: | 0.1 ml Rabbit antisera. |
| Uses: | Optimal working dilutions should be determined experimentally by the investigator. Prepare working dilution immediately before use. Suggested starting dilutions are as follows. Western Blot: 1:5,000 - 1:15,000 Immunoprecipitation: 1 to 4 ug/mg lysate Histo/Cytochemistry: not tested*In some cases, the antibody may be diluted further than indicated. |
| Background: | MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene. |
| Storage: | Store at 4C. Do not freeze. |
| Host_Name: | Rabbit |
| ListPrice: | 285 |
| AppSummary: | IP, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-MAD1 antibody, anti-MAD-1 antibody, anti-MADL1 antibody, anti-HsMAD1 antibody, anti-Mitotic arrest deficient-like 1 antibody, anti-PIG9 antibody, anti-p53 inducible protein 9 antibody, anti-TP53I9 antibody, anti-tumor protein p53 inducible protein 9 antibody, anti-TXBP181 antibody, anti-Tax binding protein antibody |
| ProteinTarget: | MAD-1 antibody |
| PackageSize: | 0.1 ml |
| NotesMain: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |
| Gene_Id: | 8379 |
| Omim_ID: | NB100-570 |
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