| CatalogCode: | NB100-56890 |
| ProductName: | TIR8 Antibody |
| Product Description: | Rabbit Polyclonal anti-TIR8 |
| Clonality: | Polyclonal |
| Immunogen: | This antibody was developed against a synthetic peptide corresponding to amino acids 334-358 of human Tir8. |
| CrossReactivity: | Mouse, Human Not yet tested in other species. |
| Packaging: | 0.1 mg of Rabbit Affinity Purified |
| Uses: | WB: 0.5 ug/ml |
| Control: | human or mouse kidney |
| Background: | The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). TIR8, also know as single Ig IL-1 receptor, is a member of the IL-1/TLR superfamily (2). TIR8 acts as intracellular decoy to inhibit NF-kappaB activation by members of the IL-1/TLR family (3, 4). |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Affinity Purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | PBS containing 0.2% gelatin and 0.05% sodium azide is highly toxic. |
| ListPrice: | 295 |
| AppSummary: | WB |
| SpeciesSummary: | Hu, Mu |
| ALTnames: | anti-Toll antibody, anti-IL-1R8 antibody, anti-Ig IL-1-related Receptor antibody |
| ProteinTarget: | TIR8 |
| PackageSize: | 0.1 mg |
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