| Catalog Code: | NB100-56725 |
| Product Type: | Primary Antibody |
| Product Name: | D4-GDI Antibody |
| List Price: | 295 |
| Clonality: | Monoclonal |
| Gene ID: | 396 |
| Host: | Mouse |
| Clone: | 97A1015 |
| Isotype: | IgG2b, k |
| Product Description: | Mouse Monoclonal anti-D4-GDI (97A1015) |
| Cross Reactivity: | Human, Mouse Not yet tested in other species. |
| Species Summary: | Hu, Mu |
| Background: | D4-GDI (GDP dissociation inhibitor) is a negative regulator of the ras-related Rho family of GTPases. Since the Rho GTPases promote cytoskeletal and membrane changes associated with apoptotic cell death, the removal of the D4-GDI block through its cleavag |
| Immunogen: | A synthetic peptide corresponding to the region of the Fas-induced cleavage site of human D4-GDI was used as the immunogen. |
| Specificity: | In anti-Fas treated Jurkat, a ~23 kDa band should be observed. |
| Purity: | Affinity Purified |
| Buffer: | PBS containing 0.02% sodium azide. Sodium azide is highly toxic. |
| Packaging: | 0.1mg of Mouse Affinity Purified |
| Package Size: | 0.1 mg |
| Uses: | WB: 2 ug/ml ~; Flow (Intracellular): 0.5-1 ug/ 1x10; 6 cells ~; IP: 1-2 ug/ml ~; IHC: 2 ug/ml |
| Application Summary: | FACS, IHC, IP, WB |